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Photo of Kevin Plaxco

Kevin Plaxco

ICB Biotechnology Tools Co-Leader
Director, Center for Bioengineering 
Professor
Chemistry & Biochemistry
UC Santa Barbara
Phone:
+1 805-893-5558
Email:
kwp@chem.ucsb.edu
Website:
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We are developing a broad class of optical and electronic (electrochemical) biosensors based on the binding-induced folding of proteins, peptides and DNA. These sensors are sensitive (to femtomolar), specific, rapid (minutes) and selective enough to deploy directly in serum, foodstuffs and other grossly contaminated materials.

Displaying 21 - 25 of 25

ICB Supported Publications

Quantification of transcription factor binding in cell extracts using an electrochemical, structure-switching biosensor

A. Bonham, K. Hsieh, B. Ferguson, A. Vallée-Bélisle, F. Ricci, H. Soh, and K. Plaxco
Journal of the American Chemical Society,
10.1021/ja2115663

Polarity-switching electrochemical sensor for specific detection of single-nucleotide mismatches

K. Hsieh, R. White, B. Ferguson, K. Plaxco, Y. Xiao, and H. Soh
Angewandte Chemie International Edition,
10.1002/ange.201103482

Two-step, PCR-free telomerase detection by using exonuclease III-aided target recycling

X. Zuo, F. Xia, A. Patterson, H. Soh, Y. Xiao, and K. Plaxco
ChemBioChem,
10.1002/cbic.201100592

An electrochemical supersandwich assay for sensitive and selective DNA detection in complex matrices

Xia, F., White, R., Zuo, X., Patterson, A., Xiao, Y., Kang, D., Gong, X., Plaxco, K., Heeger
Journal of the American Chemical Society,
10.1021/ja104998m

Colorimetric detection of DNA, small molecules, proteins, and ions using unmodified gold nanoparticles and conjugated polyelectrolytes

Xia, F., Zuo, X., Yang, R., Xiao, Y., Kang, D., Vallée-Bélisle, A., Gong, X., Yuen, J.D., Hsu, B.Y., Heeger, A., Plaxco, K.
Proceedings of the National Academy of Sciences,
10.1073/pnas.1005632107
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