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Photo of Irene Chen

Irene Chen

Assistant Professor
Chemistry & Biochemistry
UC Santa Barbara
Phone:
+1 805-893-8364
Email:
chen@chem.ucsb.edu
Website:
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Principles of molecular life and biochemical systems. Synthetic biology, molecular fitness landscapes, artificial life and origin of life, chemical biology.

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Displaying 1 - 8 of 8

ICB Supported Publications

Molecular Fitness Landscapes from High-Coverage Sequence Profiling

Celia Blanco, Evan Janzen, Abe Pressman, Ranajay Saha and Irene A. Chen
Annual Reviews of Biophysics,
10.1146/annurev-biophys-052118-115333

Lipid vesicles chaperone an encapsulated RNA aptamer

Ranajay Saha, Samuel Verbanic and Irene A. Chen
Nature Communications,
10.1038/s41467-018-04783-8

Analysis of in vitro evolution dynamics estimates ribozyme rates and the underlying distribution of activity among random sequences

Pressman, A., Moretti, J.E., Campbell, G.W., Muller, U.F. and Chen, I.A.
Nucleic Acids Research ,
10.1093/nar/gkx540

Quantitative analysis of synthesized nucleic acid pools

Xulvi-Brunet, R., Campbell, G.W., Rajamani, S., Jimenez, J. I. and Chen, I. A.
Nonlinear Dynamics in Biological Systems,
10.1007/978-3-319-33054-9_2

Computational analysis of fitness landscapes and evolutionary networks from in vitro evolution experiments

Xulvi-Brunet, R., Campbell, G.W., Rajamani, S., Jimenez, J. I. and Chen, I. A.
Methods,
dx.doi.org/10.1016/j.ymeth.2016.05.012

The RNA world as a model system to study the origin of life

Pressman, A., Blanco, C. and Chen, I. A.
Current Biology,
10.1016/j.cub.2015.06.016

Molecular crowding and early evolution

R. Saha, A. Pohorille, and I. A. Chen
Origins of Life and Evolution of Biospheres,
10.1007/s11084-014-9392-3

Experimental fitness landscapes to understand the molecular evolution of RNA-based life

S. S. Athavale, B. Spicer, and I. A Chen
Current Opinion in Chemical Biology,
10.1016/j.cbpa.2014.09.008
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